Clexane 4000 IU/0.4 prefilled syringes

Clexane 4000 IU/0.4 Prefilled Syringes:

What is enoxaparin and what are its uses:

• Enoxaparin sodium is low molecular weight heparin (LMWH).

Enoxaparin works in two ways:

• Stop the increase in the size of clots in the blood. This helps your body break them down and prevent them from causing you harm
• Stopping the formation of blood clots in the blood.

Enoxaparin can be used:

•  Treating blood clots in the blood.
• Stop the formation of blood clots in the blood in the following cases:
• Before and after the operation
• When you have an acute illness and are experiencing a period of limited mobility
• When you have unstable angina (a condition in which not enough blood reaches your heart)
• After a heart attack
• Stopping the formation of blood clots in the tubing of a dialysis machine (used for people with severe kidney problems).

What you need to know before using enoxaparin:

Do not use enoxaparin:

• If you are allergic to enoxaparin sodium or any of the other ingredients of this medication
• If you are allergic to heparin or other low molecular weight heparins such as nadroparin, tinzaparin, or dalteparin.
• If you have had a reaction to heparin that caused a severe decrease in the number of clotting cells (platelets) - this reaction is called heparin-induced thrombocytopenia - within the last 100 days or
• If you have antibodies against enoxaparin in your blood.
•  If you have severe bleeding or have a condition that has a high risk of bleeding (such as a stomach ulcer, recent surgery of the brain or eyes), including a recent bleeding stroke.
•  If you are using enoxaparin to treat blood clots in your body you will receive a spinal or epidural anesthesia or lumbar puncture within 24 hours.

Warnings and precautions:

Talk to your doctor or pharmacist before using enoxaparin if:

• You have had a reaction to heparin in the past that caused a severe drop in your platelet count
• You will receive spinal or epidural anesthesia or a lumbar puncture
• A heart valve was installed
• You have endocarditis (inflammation of the inner lining of the heart)
•  You have a history of stomach ulcers
• I recently had a stroke
• You have high blood pressure
•  You have diabetes or problems with blood vessels in the eye due to diabetes (called diabetic retinopathy)
• You recently had surgery on your eyes or brain
•  Being elderly (over 65 years of age), especially if you are over 75 years old
•  You have kidney problems
• You have liver problems
• You are underweight or overweight
•  You have a high level of potassium in your blood (this can be checked with a blood test)
• You are currently using medications that affect bleeding.

Other medicines and enoxaparin:

It is especially important to tell your doctor if you are taking any of the following:

• Warfarin - used to thin the blood
• Aspirin (also known as acetylsalicylic acid or ASA), clopidogrel, or other medications used to stop blood clots from forming
•  Dextran injection - used as a blood substitute
• Ibuprofen, diclofenac, ketorolac or other medicines known as NSAIDs that are used to treat pain and swelling in arthritis and other conditions
• Prednisolone, dexamethasone or other medications used to treat asthma, rheumatoid arthritis, and other conditions
• Medications that raise the level of potassium in the blood such as potassium salts, water pills, and some medications for heart problems.

How to use Enoxaparin:

Always take your medication exactly as your doctor tells you to. If you are not sure how to take the tablets, ask your doctor or pharmacist.

Taking this medicine:

•  Your doctor or nurse will usually give you enoxaparin. This is because it needs an injection.
•  When you go home, you may need to continue using enoxaparin and give it on your own
•  Enoxaparin is given by subcutaneous (under the skin) injection.
• Enoxaparin may be given by injection into a vein (into a vein) after certain types of heart attacks and surgeries.
• Enoxaparin may be added to the tube leaving the body (arterial line) at the beginning of a dialysis session.
• Do not inject enoxaparin into a muscle.

How much will be given to you:

• Your doctor will decide how much enoxaparin to give you. The amount will depend on the reason for using it.
• If you have kidney problems, you may be given a smaller amount of enoxaparin.

How to give yourself an enoxaparin injection:

•  If you can give yourself enoxaparin, your doctor or nurse will show you how to do this. Do not try to inject yourself if you have not been trained how to do so.
• If you are not sure what to do, talk to your doctor or nurse straight away. Properly administering the injection under the skin (called a “subcutaneous injection”) helps reduce pain and bruising at the injection site.

Use in children and adolescents: 

• The safety and effectiveness of enoxaparin have not been evaluated in children or adolescents.

Possible side effects:

• Like other similar medicines (medicines to reduce blood clotting), enoxaparin may cause bleeding which may be life-threatening. In some cases, bleeding may not be obvious.
• If you experience any bleeding event that does not stop on its own or if you experience signs of excessive bleeding (exceptional weakness, fatigue, paleness, dizziness, headache or unexplained swelling), consult your doctor immediately.
• Your doctor may decide to keep you under close monitoring or change your medication.

Stop using enoxaparin and talk to your doctor or nurse straight away if:

• You have any signs of a severe allergic reaction (such as difficulty breathing, swelling of the lips, mouth, throat or eyes).

You should tell your doctor immediately

• If you have any sign of blood vessel blockage caused by a blood clot such as:
• Cramping, redness, warmth or swelling in one of your legs - these are symptoms of deep vein thrombosis
• Shortness of breath, chest pain, fainting or coughing up blood - these are symptoms of pulmonary embolism
• If you have a painful rash of dark red spots under the skin that do not go away when you press on them.
• Your doctor may ask you to have a blood test to check your platelet count.