Dexilant 30 mg 28 capsules

Dexilant 30 mg 28 capsules:

Dexlansoprazole 30 mg delayed-release capsules.

Dexlansoprazole is used for:

It is a proton pump inhibitor (PPI).
Delayed capsules are indicated in adults for:

• Cure all degrees of erosive esophagitis (erosive esophagitis).
  
•  Maintains healing of erosive esophagitis and relieves heartburn.
  
•  Treating heartburn associated with asymptomatic gastroesophageal reflux disease (GERD).
  
• SoluTab delayed-release orally disintegrating tablets are indicated when 
  
• Maintains healing of erosive esophagitis and relieves heartburn.
  
• Treating heartburn associated with esophageal reflux.
  

Do not use dexlansoprazole:

• Patients suffering from hypersensitivity to any of the components of the preparation.
  
• Patients receiving products containing rilpivirine.

Warnings and precautions:

•  Gastric malignancy: Symptomatic response with dexlansoprazole does not preclude gastric malignancy
   
• Acute interstitial nephritis: observed in patients taking proton pump inhibitors
  
•  Cyanocobalamin (vitamin B12) deficiency: Long-term daily use (e.g., longer than 3 years) may result in malabsorption or cyanocobalamin deficiency.
  
•  Clostridium difficile associated diarrhea: Proton pump inhibitor therapy may be associated with an increased risk
  
•  Bone fracture: Long-term, multiple daily proton pump inhibitor therapy may be associated with an increased risk of osteoporosis-related fractures of the hip, wrist, or spine.
  
• Hypomagnesemia: Rarely reported with prolonged treatment with proton pump inhibitors.
  
•  Interactions with Diagnostic Investigations for Neuroendocrine Tumors: Increases in intragastric pH may lead to hypergastrinemia, hyperplasia of chromaffin-like cells, and increased chromogrin A levels that may interfere with diagnostic investigations for neuroendocrine tumors.
  
•  Interaction with Methotrexate: Concomitant use with proton pump inhibitors may elevate and/or prolong the serum concentrations of methotrexate and/or its metabolite, potentially resulting in toxicity. With high-dose methotrexate administration, consider temporary withdrawal.

Possible side effects:

Stop using the product and seek immediate medical attention if you

• You suffer from: tightness in the throat, swelling of the eyes, face, lips or tongue, or you feel faint or have difficulty breathing.
•  Hives or itching of the face or body.

Other medicines and dexlansoprazole:

Tell your doctor or pharmacist if you are taking:

•  Antiretrovirals
  
•  Warfarin
  
• Methotrexate
  
•  Digoxin
•  Drugs that depend on gastric pH for absorption (such as iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole/itraconazole)
  
• Tacrolimus
  
• Inhibitors of CYP2C19 or CYP3A4
• Inducers of CYP2C19 or CYP3A4

 How to use dexlansoprazole:

• Two 30 mg SoluTab tablets cannot be substituted for one 60 mg capsule
  
• Dexlansoprazole capsules
  
• Healing of erosive esophagitis: 60 mg once daily for up to 8 weeks
  
• Maintenance of healing of erosive esophagitis: 30 mg once daily for up to 6 months
  Asymptomatic esophageal reflux: 30 mg once daily for
• 4 weeks
  Dixlansoprazole SoluTab
  
• Maintenance of healing of erosive esophagitis: 30 mg once daily for up to 6 months
  
•  Asymptomatic esophageal reflux: 30 mg once daily for 4 weeks

Dexlansoprazole capsules:

• Eat without regard.
  
•  Swallow whole; Do not chew.
  
• Dixlansoprazole SoluTab.
  
• Take at least 30 minutes before a meal.