Novonorm 0.5 mg 30 tablets

Novonorm 0.5 mg 30 tablets:

Repaglinide 0.5 mg tablets.

What is Repaglinide and what is it used for?

• Repaglinide is an oral antidiabetic medication.
• It helps the pancreas produce more insulin and thus lower blood sugar (glucose).

How to take repaglinide:

• The normal starting dose is 0.5 mg before each main meal.
• Swallow the tablets with a glass of water immediately before or up to 30 minutes before each main meal.
• The dose may be adjusted by your doctor up to 4 mg to be taken immediately before or up to 30 minutes before each main meal.
• The maximum recommended daily dose is 16 mg.

Do not take repaglinide:

• If you are allergic to repaglinide or to any of the other ingredients in this medication.
• If you have type 1 diabetes.
• If the acidity level in the body increases (diabetic ketoacidosis).
• If you have severe liver disease.
• If you are taking gemfibrozil (a medicine used to lower excess fat levels in the blood).

Warnings and precautions:

• Talk to your doctor or pharmacist before taking repaglinide:
• If you have liver problems. Repaglinide is not recommended for patients with moderate liver disease. Repaglinide should not be taken if you have severe liver disease.
• If you have kidney problems. Repaglinide should be taken with caution.
• If you are about to have major surgery or have recently suffered from a serious illness.
• If you are under 18 years old or over 75 years old. Repaglinide is not recommended.

Possible side effects of repaglinide:

Hypoglycemia:

• The most common side effect is hypoglycemia which may affect up to 1 in 10 patients.
• Hypoglycemic reactions are generally mild/moderate but may occasionally progress to loss of consciousness or coma due to hypoglycemia. If this happens, call medical help immediately.

sensitive:

• Allergies are very rare (may affect up to 1 in 10,000 patients). Symptoms such as swelling, difficulty breathing, rapid heartbeat, feeling dizzy, and sweating can be signs of an allergic reaction. Call your doctor immediately.
• Other side effects:
• stomach ache
• Diarrhea.
• Rare: acute coronary syndrome (but may not be due to the drug).

Other medicines and repaglinide:

• Your body's response to repaglinide may change if you take other medicines, especially these:
• monoamine oxidase inhibitors 
• Beta blockers (used to treat high blood pressure or heart disease)
• Angiotensin-converting enzyme inhibitors (used to treat heart disease)
• Salicylates (such as aspirin)
• Octreotide (used to treat cancer).
• Non-steroidal anti-inflammatory drugs 
• Steroids (anabolic steroids and corticosteroids – used for anemia or to treat inflammation)
• Oral contraceptives (birth control pills)
• Thiazides (diuretics or "water pills")
• Danazol (used to treat breast cysts and endometriosis)
• Thyroid products (used to treat low levels of thyroid hormones)
• Sympathomimetics (used to treat asthma)
• Clarithromycin, trimethoprim, rifampicin (antibiotic medicines)
• Itraconazole, ketoconazole (antifungal medicines)
• Gemfibrozil (used to treat high blood fats).
• Cyclosporine (used to suppress the immune system)
• Deferasirox (used to reduce chronic iron overload)
• Phenytoin, carbamazepine, phenobarbital (used to treat epilepsy)
• St. John's Wort (herbal medicine)
• Clopidogrel (prevents blood clotting)