Downyl M 2.5/500 mg 30 tablets

Downyl M 2.5/500 mg 30 tablets

Glibenclamide/metformin hydrochloride 2.5 mg/500 mg tablets

Glibenclamide/metformin hydrochloride combination is used to lower blood sugar levels in type 2 (non-insulin dependent) diabetes.

How to use:

• This property is intended for adults only.
• Take this drug with food.
• The usual starting dose is glibenclamide 1.25-2.5 mg/metformin 500-1000 mg. It is given once or twice daily.
• Take this drug as ordered by your doctor.

side effects:

Stop using this product and seek immediate medical attention if you develop a rash; Itch; red, blistered, or peeling skin; tightness in the chest or throat; difficulty breathing, swallowing, or speaking; Unusual hoarseness or swelling of the mouth, face, lips, tongue, or throat.

Serious side effects:

• Low blood sugar levels.
• Liver problems.
• Allergic reactions.

Do not take the medicine in cases including:

• If you are allergic to any ingredients of this medication such as glibenclamide, metformin, other sulfonylureas, sulfonamides or any of the other ingredients.
• If you have type 1 (insulin-dependent) diabetes.
• If you suffer from serious liver problems.
• If you have kidney problems.
• If you are dehydrated (you have lost a lot of water from your body due to long-term or severe diarrhea, or if you have vomited several times in a row).
• If you have a severe infection, such as one that affects the lungs or kidneys.
• If you have severe heart failure or have recently had a heart attack, have serious blood vessel problems or have breathing difficulties.
• If you take a medicine called bosentan for high blood pressure.
• If you consume a lot of alcohol.

Warnings and precautions:

Tell your doctor about all your health conditions, including, if you have:

• If you are recovering from an injury, operation, infection, fever, or other forms of stress.
• If you suffer from liver or kidney problems.
• If you suffer from heart disease.
• If you have a deficiency of an enzyme called glucose-6-phosphate dehydrogenase (G6PD).
• You should stop taking this medicine for a period of time before having major surgery. Talk to your doctor.
• This medication may cause low blood sugar, especially if you miss a meal, exercise too much, or drink alcohol.

Signs of low blood sugar include nausea, hunger, tremors, dizziness, confusion, drowsiness, difficulty speaking, and sweating.

Interaction with other medications:

*Other medicines used for diabetes.

*Some high blood pressure medications.

*Contraceptive pills.

*Medicines to treat mood disorders.

*Some antibiotics.

*Steroid-free anti-inflammatory medications.

*Corticosteroids.

* Anticoagulants such as warfarin.

*Phenytoin.

*Digoxin.

How to store the medicine:

• Store at room temperature 68 to 77°F (20 to 25°C).
• Keep this medicine out of the reach of children.
• Do not use this medicine after the expiry date stated on the package.