Desmopressin 120 mcg orally
Why is desmopressin used:
Desmopressin is a synthetic synthetic analogue of the natural pituitary hormone arginine vasopressin. The difference is that the cysteine is deaminated and L-arginine is replaced with D-arginine.
It is prescribed to treat:
• Primary nocturnal enuresis (bedwetting) in children (from the age of 5 years) and adults (up to the age of 65 years).
Do not use desmopressin:
• Habitual or psychogenic polydipsia (resulting in urine output exceeding 40 ml/kg/24 hours)
• History of known or suspected heart failure and other conditions requiring treatment with diuretics
• Moderate and severe renal insufficiency (creatinine clearance less than 50 ml/min)
• Known hyponatremia
• Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
• Hypersensitivity to desmopressin or any of the excipients
Warnings and precautions:
Pay close attention:
• If you suffer from a disease that causes fluid and/or electrolyte imbalance, for example. Vomiting, diarrhea, systemic infections, fever or gastroenteritis
• If you have a medical condition that could be worsened by fluid and/or electrolyte disturbance
• If you have cystic fibrosis
• If you have difficulty urinating
Possible side effects:
Stop using the product and seek immediate medical attention if you experience tightness in the throat, swelling of the eyes, face, lips, or tongue, feel faint, or have difficulty breathing. Stop using the product if you experience hives or itching of the face or body.
Other medicines and desmopressin:
Please inform your doctor or pharmacist:
• If you are taking, have recently taken or used any other medicines, even those that have not been prescribed for you
• If you are taking medication to treat depression. Epilepsy or type 2 diabetes
• If you are taking pain and/or inflammation medication that contains non-steroidal anti-inflammatory drugs (also known as NSAIDs)
• If you are taking a medicine containing loperamide for diarrhoea
How to use desmopressin:
The usual starting dose is 120 mcg sublingually (under the tongue) at bedtime. Depending on how well your bedwetting is controlled, your doctor may increase your dose to either 120 mcg or 240 mcg sublingually (under the tongue) at bedtime. The need for continued treatment is usually checked every three months.
How to store desmopressin:
Store at a temperature below 25 degrees Celsius. Store in its original packaging to protect it from moisture and light.
Keep out of the sight and reach of children. Do not take this medicine after the expiry date stated on the package.
The expiry date refers to the last day of the same month. Do not dispose of medicines in wastewater or household waste.