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The active substance is Etoricoxib.
Etoricoxib is one of a group of medicines called selective COX-2 inhibitors.
These drugs belong to a family of medicines called non-steroidal anti-inflammatory drugs (NSAIDs).
Etoricoxib helps reduce pain and swelling (inflammation) in the joints and muscles in people aged 16 years and older who suffer from osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gout.
Etoricoxib is also used to treat short-term moderate pain after dental surgery in people aged 16 years and older.
Osteoporosis
Osteoarthritis is a disease that affects the joints.
It results from the gradual breakdown of the cartilage that lines the ends of the bones.
This causes swelling (inflammation), pain, tenderness, stiffness, and disability.
Rheumatoid arthritis
Rheumatoid arthritis is a long-term inflammatory disease affecting the joints.
It causes pain, stiffness, swelling, and increasing loss of movement in the affected joints.
It may also cause inflammation in other parts of the body.
Gout
Gout is a disease that causes sudden and recurrent attacks of extremely painful joint inflammation and redness.
It occurs due to the deposition of mineral crystals in the joint.
Ankylosing spondylitis
Ankylosing spondylitis is an inflammatory disease affecting the spine and large joints.
Do not use etoricoxib:
If you are hypersensitive (allergic) to etoricoxib or any of the other ingredients of this medicine
If you are allergic to non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin and COX-2 inhibitors
If you currently have a stomach ulcer or bleeding in the stomach or intestines
If you suffer from serious liver diseases
If you suffer from serious kidney disease
If you are pregnant, may be pregnant, or breastfeeding
If you are under 16 years old
If you suffer from inflammatory bowel disease, such as Crohn's disease, ulcerative colitis, or colitis
If you suffer from high blood pressure that is not controlled by treatment (consult your doctor or nurse if you are not sure your blood pressure is adequately controlled)
If your doctor has diagnosed heart problems including heart failure (moderate or severe types), angina (chest pain)
If you have had a heart attack, undergone bypass surgery, or have peripheral artery disease (poor circulation in the legs or feet due to narrowed or blocked arteries)
If you have had any type of stroke (including a mini-stroke or transient ischemic attack). Etoricoxib may slightly increase the risk of heart attack and stroke, which is why it should not be used by those who have already had heart problems or a stroke.
You should inform your doctor of the following:
You have a history of bleeding or stomach ulcers.
You are dehydrated, for example due to a prolonged episode of vomiting or diarrhea.
You have swelling due to fluid retention.
You have a history of heart failure or any other form of heart disease.
You have a history of high blood pressure. Etoricoxib can increase blood pressure in some people, especially at high doses, and your doctor will want to check your blood pressure from time to time.
You have a history of liver or kidney disease.
You are receiving treatment for an infection. ETORICOXIB can mask or hide fever, which is a sign of infection.
If you have diabetes, high cholesterol, or are a smoker, this may increase your risk of heart disease.
You are a woman trying to conceive.
You are over 65 years old.
Please inform your doctor or pharmacist if you are taking, have recently taken, or may take any other medicines, including those obtained without a prescription.
Drugs that thin the blood (anticoagulants), such as warfarin
Rifampicin (antibiotic)
Methotrexate (a drug used to suppress the immune system, often used in rheumatoid arthritis)
Cyclosporine or tacrolimus (drugs used to suppress the immune system)
Lithium (medicine used to treat certain types of depression)
Medicines used to help control high blood pressure and heart failure are called angiotensin-converting enzyme inhibitors and angiotensin receptor blockers, examples include enalapril, ramipril, losartan, and valsartan.
Diuretics (water tablets)
Digoxin (medicine used to treat heart failure and irregular heartbeats)
Minoxidil (medicine used to treat high blood pressure)
Salbutamol tablets or oral solution (medicine for asthma)
Contraceptive pills (combining them may increase the risk of side effects)
Hormone replacement therapy (combining them may increase the risk of side effects)
Aspirin, the risk of stomach ulcers is higher if you take Etoricoxib with aspirin.
Aspirin for the prevention of heart attacks or strokes: Etoricoxib can be taken with a low dose of aspirin.
If you are currently taking a low dose of aspirin to prevent heart attacks or strokes, you should not stop taking aspirin until you have talked to your doctor.
Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs):
Do not take high doses of aspirin or any other anti-inflammatory medicines while taking Etoricoxib.
Always take this medicine exactly as your doctor has told you.
If you are unsure, consult your doctor or pharmacist.
Do not take a higher dose than the dose recommended for your condition.
Your doctor may want to discuss your treatment from time to time.
Use the lowest dose that controls the pain.
You should not take Etoricoxib for longer than necessary.
This is because the risk of heart attacks and strokes may increase after long-term treatment, especially at high doses.