Blopress Plus 8/12.5mg 28 tablets

Blopress Plus 8/12.5mg 28 Tablets:

Blopress Plus tablets belong to antihypertensive medications.

How candesartan and hydrochlorothiazide work:

• Candesartan is an angiotensin II receptor blocker (ARB) that works by blocking the effect of angiotensin II in the body, which causes blood vessel constriction.
• As a result, candesartan relaxes blood vessels, lowering blood pressure and increasing the supply of blood and oxygen to the heart.
• Hydrochlorothiazide inhibits the transport of sodium chloride into the blood, causing more sodium to be excreted in the kidneys along with the accompanying fluid, thus increasing diuresis, which in turn reduces blood volume and ultimately blood pressure.
• With long-term use, sustained reduction of arterial pressure by a thiazide diuretic (TZD) is thought to occur through a decrease in vascular resistance.

Uses of Blopress Plus:

• Treatment of hypertension in adult patients when monotherapy with candesartan cilexetil or hydrochlorothiazide alone is insufficient.
• High blood pressure is a common condition in which the long-term force of blood pressure against the walls of your arteries is high enough that it can eventually cause health problems, such as heart disease.
• Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular diseases, especially strokes and myocardial infarction.

How to use Blopress Plus:

• Always take this medication exactly as your doctor has told you. Consult your doctor or pharmacist if you are not sure.
• The tablets should be swallowed whole with a glass of water.
• You should try to take your daily dose at around the same time every day.
• You should continue taking the medication until your doctor tells you otherwise.
• Do not break the tablet in half.
• You can take the tablets with or without food.
• The recommended dose is one tablet once daily, but your doctor may increase the dose to reach your target blood pressure.
• Doses may be changed in special circumstances, so always follow your doctor or pharmacist's instructions.
• If you take more medicine than you should, talk to your doctor or go to hospital straight away.
• If you forget to take a dose, take it as soon as you remember unless it is almost time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for a missed dose.

Do not use Blopress:

•  If you have: hypersensitivity to the active substance or to any of the other ingredients of the medicine or to medicines derived from sulfonamides (hydrochlorothiazide is a medicine derived from sulfonamides).

Warnings and precautions:

Talk to your doctor about all your medical conditions before taking this medication including:

• If you have kidney problems.
• If you have liver problems.
• If you have heart problems or heart failure.
• If you have gout.
• If you suffer from diabetes.
• If you are vomiting or have recently had severe vomiting or diarrhea.
• If you have low blood pressure.
• If you have had a heart attack or stroke.
• If you are taking any of the following medications: angiotensin-converting enzyme inhibitors (such as enalapril, lisinopril, ramipril) or aliskiren.
• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby.

side effects:

In controlled clinical studies with candesartan cilexetil/hydrochlorothiazide, adverse events were mild and transient and included:

• Blood and lymphatic system disorders: leukopenia, neutropenia, agranulocytosis.
• Metabolic and nutritional disorders: hyperkalemia and hyponatremia.
• Nervous system disorders: dizziness, headache.
• Gastrointestinal disorders: nausea.
• Hepatobiliary disorders: increased liver enzymes, abnormal liver function or hepatitis.
• Skin and subcutaneous tissue disorders: angioedema, rash, urticaria, pruritus.
• Musculoskeletal, connective tissue and bone disorders: back pain, joint pain and muscle pain.
• Renal and urinary disorders: Renal impairment, including renal failure in susceptible patients.

the components:

• Candesartan 8 mg + hydrochlorothiazide 12.5 mg tablets.