Novonorm 1 mg 30 tablets:
Repaglinide 1 mg tablets.
What is Repaglinide and what is it used for?
- Repaglinide is an oral antidiabetic medication.
- It helps the pancreas produce more insulin and thus lower blood sugar (glucose).
How to take repaglinide:
- The normal starting dose is 0.5 mg before each main meal.
- Swallow the tablets with a glass of water immediately before or up to 30 minutes before each main meal.
- The dose may be adjusted by your doctor up to 4 mg to be taken immediately before or up to 30 minutes before each main meal.
- The maximum recommended daily dose is 16 mg.
Do not take repaglinide:
- If you are allergic to repaglinide or to any of the other ingredients in this medication.
- If you have type 1 diabetes.
- If the acidity level in the body increases (diabetic ketoacidosis).
- If you have severe liver disease.
- If you are taking gemfibrozil (a medicine used to lower excess fat levels in the blood).
Warnings and precautions:
- Talk to your doctor or pharmacist before taking repaglinide:
- If you have liver problems. Repaglinide is not recommended for patients with moderate liver disease. Repaglinide should not be taken if you have severe liver disease.
- If you have kidney problems. Repaglinide should be taken with caution.
- If you are about to have major surgery or have recently suffered from a serious illness.
- If you are under 18 years old or over 75 years old. Repaglinide is not recommended.
Possible side effects of repaglinide:
Hypoglycemia:
- The most common side effect is hypoglycemia which may affect up to 1 in 10 patients.
- Hypoglycemic reactions are generally mild/moderate but may occasionally progress to loss of consciousness or coma due to hypoglycemia. If this happens, call medical help immediately.
sensitive:
- Allergies are very rare (may affect up to 1 in 10,000 patients). Symptoms such as swelling, difficulty breathing, rapid heartbeat, feeling dizzy, and sweating can be signs of an allergic reaction. Call your doctor immediately.
- Other side effects:
- stomach ache
- Diarrhea.
- Rare: acute coronary syndrome (but may not be due to the drug).
Other medicines and repaglinide:
- Your body's response to repaglinide may change if you take other medicines, especially these:
- monoamine oxidase inhibitors
- Beta blockers (used to treat high blood pressure or heart disease)
- Angiotensin-converting enzyme inhibitors (used to treat heart disease)
- Salicylates (such as aspirin)
- Octreotide (used to treat cancer).
- Non-steroidal anti-inflammatory drugs
- Steroids (anabolic steroids and corticosteroids – used for anemia or to treat inflammation)
- Oral contraceptives (birth control pills)
- Thiazides (diuretics or "water pills")
- Danazol (used to treat breast cysts and endometriosis)
- Thyroid products (used to treat low levels of thyroid hormones)
- Sympathomimetics (used to treat asthma)
- Clarithromycin, trimethoprim, rifampicin (antibiotic medicines)
- Itraconazole, ketoconazole (antifungal medicines)
- Gemfibrozil (used to treat high blood fats).
- Cyclosporine (used to suppress the immune system)
- Deferasirox (used to reduce chronic iron overload)
- Phenytoin, carbamazepine, phenobarbital (used to treat epilepsy)
- St. John's Wort (herbal medicine)
- Clopidogrel (prevents blood clotting)