Primolut N Tablets - 30 Tablets

Primolut contains the active ingredient norethisterone, which is a synthetic hormone similar to the natural sex hormone progesterone. It is used in a wide range of menstrual disorders. In women, progesterone is responsible for the development of a healthy endometrium (lining of the uterus) and is essential for pregnancy. The body produces the hormone progesterone at certain times of the menstrual cycle, causing the lining of the uterus to thrive. If the fertilized egg does not attach to the lining of the uterus at the end of the monthly menstrual cycle, progesterone levels in the body will decrease. This prompts the body to shed the lining of the uterus, if the fertilized egg has successfully attached to the lining of the uterus at the end of the menstrual cycle, and progesterone levels in the body are still high. This helps maintain a healthy uterine lining for continued pregnancy.

Norethisterone can mimic the effects of your own natural hormone progesterone and so helps to regulate healthy and normal growth of the uterine lining, and can be used in the treatment of menstrual disorders such as irregular or painful menstrual periods, premenstrual syndrome and endometriosis. It may also be used to delay the onset of menstruation for special circumstances, such as if traveling or participating in a sporting event. Norethisterone is usually taken on specific days during the menstrual cycle.

What are the uses of Primolut Tablets:

Endometrial

Menstrual disorders such as painful periods (dysmenorrhea), heavy menstrual bleeding (menorrhagia), irregular, persistent, and heavy menstrual bleeding or premenstrual syndrome

delayed menstruation

Warnings when using Primolut pills:

1. Women taking contraceptives that contain a low dose of the hormone progesterone in combination with an estrogen (such as the contraceptive pill) appear to have a slightly increased risk of developing a blood clot in a vein, eg in the leg (deep vein thrombosis) or in the lungs (pulmonary embolism), or a blood clot in an artery, causing such as a stroke or heart attack. It is not known what role progesterone plays in this area. Although this medication is not a contraceptive, it does contain progesterone, so there is a possibility that it could also increase your risk of developing these types of blood clots.

2. The risk of blood clots forming in the veins (venous thromboembolism) while taking this drug may be temporarily increased if you are immobile for long periods of time, for example if you have a major accident or major surgery. For this reason, your doctor will usually recommend that you stop taking this medicine for a period of time (usually six weeks) before any planned surgery, particularly abdominal surgery or orthopedic surgery of the lower extremities (but not before minor surgery such as a tooth extraction). ). You will also need to stop taking this medicine if you are going to be immobile for long periods, for example because you are confined to bed or have a leg in a cast. You should not start taking this medication again until at least two weeks after you are fully mobile. There may also be an increased risk of blood clots in the veins if you are traveling for long periods of time where you will be sat still (more than five hours). The risk of blood clots during long flights may be reduced by appropriate exercise during the flight, perhaps by wearing elastic stockings.

3. Stop taking this medicine and inform your doctor immediately if you get any of the following symptoms while taking this medicine: stabbing pains and/or unusual swelling in one leg, pain in breathing or coughing, coughing up blood, sudden shortness of breath, sudden severe chest pain, sudden disturbance of vision, hearing or speech, sudden weakness or numbness on one side of the body, fainting, collapse (all possible signs of a blood clot), seizure, migraine or severe headache, very high blood pressure, Itching of the whole body, severe depression, or if you think you might be pregnant.

4. Consult your doctor if you develop unexplained nausea, vomiting, abdominal pain, fatigue, loss of appetite, dark urine or yellowing of the eyes or skin (jaundice) during treatment, as these may be signs of liver problems

5. This medicine may increase the level of sugar in your blood. Women with diabetes may need to monitor their blood sugar more frequently during treatment with this medicine

Use Primolut with caution in the following cases:

decreased liver function

decreased kidney function

Women with a history of depression

diabetes

heart failure

High blood pressure (hypertension).

Women who suffer from migraine.

Women with a history of or risk of blood clots in the blood vessels (thromboembolism).

asthma

Epilepsy

Do not use Primolut tablets in the following cases:

Pregnancy or suspected pregnancy

Abnormal vaginal bleeding of unknown cause

Severe arterial disease, such as one that caused a stroke or heart attack

Women with blood clots in a vein of the leg (deep vein thrombosis) or in the lungs (pulmonary embolism)

bile secretion disorders causing jaundice (eg Dubin-Johnson or Rotor syndrome)

active liver disease

History of previous or existing liver tumors

A history of severe liver disease if liver function has not returned to normal

History of jaundice, severe itching, or a rash called pregnancy herpes during a previous pregnancy, or previous sex hormone use

A rare inherited blood disorder called porphyria

Women who know they are going to undergo surgery in the next six weeks and women who are going to be immobile for a long time, for example following an accident

This medicine contains lactose and is not suitable for people with rare hereditary disorders of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption.

This medicine should not be used if you are allergic to it or any of its ingredients.

If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately

Side effects of Primolut:

Nausea

Headache/migraine

Changes in menstruation, bleeding such as irregular or sometimes stopping bleeding

change in sex drive

bloating

Water retention in body tissues (fluid retention)

breast discomfort

dizziness;

depressed mood

overweight

Skin reactions such as rash and itching

hair loss

Excessive hair growth (hirsutism)

drowsiness

difficulty sleeping (insomnia)

Liver function disorder